To make bitter or sour.
To exasperate; to irritate.
Embittered; having a sour disposition or nature.
To make someone sad, forlorn and hopeless.
To devastate or lay waste somewhere.
To abandon or forsake something.
To deprive of inhabitants.
Made unfit for habitation or use because of neglect, destruction etc.
Barren and lifeless.
Dismal or dreary.
Deserted and devoid of inhabitants.
Sad, forlorn and hopeless.