To make bitter or sour.
To exasperate; to irritate.
Embittered; having a sour disposition or nature.
To strain; make tense.
To apply with energy.
To design mechanically or artistically; fashion; mold.
To fix the mind upon (something, or something to be accomplished); be intent upon
To bend or turn; direct, as one’s course or journey.
To fix the mind on; attend to; take care of; superintend; regard.
To pretend; counterfeit; simulate.