To exasperate; to irritate.
To make bitter or sour.
Embittered; having a sour disposition or nature.
To annoy, cause discomfort or resent.
To transgress or violate a law or moral requirement.
To hurt the feelings of; to displease; to make angry; to insult.
To feel or become offended; to take insult.
To physically harm, pain.
To sin, transgress divine law or moral rules.