An unforeseen occurrence beyond one's control, such as a natural disaster.
Used other than figuratively or idiomatically: see act, of, God.
A disastrous event, especially one involving great loss of life or injury.
A drama or similar work, in which the main character is brought to ruin or otherwise suffers the extreme consequences of some tragic flaw or weakness of character.
The genre of such works, and the art of producing them.