Any path through an otherwise obstructed space.
Seat in public transport, such as a plane, train or bus, that's beside the aisle.
A clear corridor in a supermarket with shelves on both sides containing goods for sale.
A wing of a building, notably in a church separated from the nave proper by piers.
The path of a wedding procession in a church or other venue; (by extension, metonymically) marriage.
An idiomatic divide between the Republican Party and the Democratic Party, who are said to be on two sides of the aisle.
A clear path through rows of seating.
A theoretical line (physically or mentally) followed from a point of origin or towards a destination. May be relative (e.g. up, left, outbound, dorsal), geographical (e.g. north), rotational (e.g. clockwise), or with respect to an object or location (e.g. toward Boston).
Guidance, instruction.
A general trend for future action.
The work of the director in cinema or theater; the skill of directing a film, play etc.