To reduce to nothing, to destroy, to eradicate.
To render null and void; to abrogate.
To react with antimatter, producing gamma radiation and (for higher-mass reactants, especially composite particles such as protons) lighter particles (such as pions, muons, and neutrinos).
To go bad, to spoil.
To win by 30 or more points.
To defeat so badly as to prevent any opposing points.
A walkover victory in sports or board games, as when the opposing side is unable to score.
Any of various small mammals, of the family Mephitidae, native to North and Central America, having a glossy black with a white coat and two musk glands at the base of the tail for emitting a noxious smell as a defensive measure.
A win by 30 or more points. (A double skunk is 60 or more, a triple skunk 90 or more.)
A member of a hybrid skinhead and punk subculture.
Any of the strains of hybrids of Cannabis sativa and Cannabis indica that may have THC levels exceeding those of typical hashish.
A despicable person.
Anything very bad; a stinker.