An uneasy or distressing desire (for something).
An unpleasant state of mental uneasiness, nervousness, apprehension and obsession or concern about some uncertain event.
A state of restlessness and agitation, often accompanied by a distressing sense of oppression or tightness in the stomach.
unhappiness, woe
(usually in plural) An instance or cause of unhappiness.
To feel grief over; to mourn, regret.
To feel or express grief.