An uneasy or distressing desire (for something).
An unpleasant state of mental uneasiness, nervousness, apprehension and obsession or concern about some uncertain event.
A state of restlessness and agitation, often accompanied by a distressing sense of oppression or tightness in the stomach.
Great sadness or distress; a misfortune causing such sadness.
A curse; a malediction.
Calamity, trouble.