anxiogenic vs irritating

anxiogenic

adj
  • Causing anxiety, or pertaining to the causing of anxiety. 

noun
  • An anxiogenic drug: a drug that causes anxiety. 

irritating

adj
  • Causing irritation, annoyance or pain. 

  • Stimulating or exciting a response. 

How often have the words anxiogenic and irritating occurred in a corpus of books? (source: Google Ngram Viewer )