Major, important.
Of or relating to an artery.
A through road.
Of considerable or relatively great size or extent.
That is large (the manufactured size).
Crossing the line of a ship's course in a favorable direction; said of the wind when it is abeam, or between the beam and the quarter.
Before the wind.
One of several common sizes to which an item may be manufactured.
A thousand dollars/pounds.
One who fits an item of that size.
An item labelled or denoted as being that size.