Major, important.
Of or relating to an artery.
A through road.
To a very great extent; total, utter.
Very large or bulky and heavy and solid.
Outstanding, beautiful.
Not having an obvious crystalline structure.
Having any mass.
Having a large mass.
Of particularly exceptional quality or value; awesome.
Affecting a large portion of the body, or severe.
Homogenous, unstructured.
Very large in size or extent.
A group of people from a locality, or sharing a collective aim, interest, etc.
A homogeneous mass of rock, not layered and without an obvious crystal structure.