Major, important.
Of or relating to an artery.
A through road.
Large; bulky.
Firm; resolute; dauntless.
Materially strong, enduring.
Obstinate.
To persist, endure.
Gadfly.
Gnat.
A large clothing size.
A dark and strong malt brew made with toasted grain.
An obese person.
Firefly or miller (moth).