Major, important.
Of or relating to an artery.
A through road.
Of or relating to a superlative.
Exceptionally good; of the highest quality; superb.
The extreme (e.g. highest, lowest, deepest, farthest, etc) extent or degree of something.
An adjective used to praise something exceptional.
The form of an adjective that expresses which of several items has the highest degree of the quality expressed by the adjective; in English, formed by appending "-est" to the end of the adjective (for some short adjectives only) or putting "most" before it.