Major, important.
Of or relating to an artery.
A through road.
Large in scope.
Of or supporting a greater range of text characters than can fit into the traditional 8-bit representation.
Antagonistic, provocative.
Operating at the side of the playing area.
Having a large physical extent from side to side.
On one side or the other of the mark; too far sideways from the mark, the wicket, the batsman, etc.
A ball that passes so far from the batsman that the umpire deems it unplayable; the arm signal used by an umpire to signal a wide; the extra run added to the batting side's score
away from or to one side of a given goal
completely
extensively
So as to leave or have a great space between the sides; so as to form a large opening.