Too irrational to be dealt with sanely.
Used as an intensifier, particularly for insane or synonyms.
Crazy.
Intoxicated by eating locoweed.
To render insane.
To poison with the loco plant; to affect with locoism.
A direction in written or printed music to be returning to the proper pitch after having played an octave higher or lower.
A certain species of Astragalus or Oxytropis, capable of causing locoism.
A locomotive.