Bitterness of temper; ill humour; irascibility.
A bitter brownish-yellow or greenish-yellow secretion produced by the liver, stored in the gall bladder, and discharged into the duodenum where it aids the process of digestion.
Two of the four humours, black bile or yellow bile, in ancient and medieval physiology.
A fit of immoderate laughter or merriment.
In vertebrates, including humans, a ductless vascular gland, located in the left upper abdomen near the stomach, which destroys old red blood cells, removes debris from the bloodstream, acts as a reservoir of blood, and produces lymphocytes.
To remove the spleen, or, by extension, to gore.
To excise or remove.
To annoy or irritate.
To complain; to rail; to vent one's spleen.