Extremely drunk.
So intoxicated as to appear to have difficulty seeing.
Drunk.
Covered with a topping or toppings.
Having a live round of ammunition in the chamber.
Equipped with numerous options.
Pertaining to a situation where there is a runner at each of the three bases.
Designed to produce a predictable answer, or to lay a trap.
Weighted with lead or similar.
Burdened by some heavy load; packed.
Having strong connotations that colour the literal meaning and are likely to provoke an emotional response. Sometimes used loosely to describe a word that simply has many different meanings.
Of a die or dice: weighted asymmetrically, and so biased to produce predictable throws.
Possessing great wealth.