Being very important, or key to something.
Having or containing the centre of something.
Being in the centre.
Exerting its action towards the peripheral organs.
centre
Expressing some intention or significance; meaningful.
Having a (specified) intention.
The connotation associated with a word, expression, or symbol.
The denotation, referent, or idea connected with a word, expression, or symbol.
Intention.
The purpose, value, or significance (of something) beyond the fact of that thing's existence.