Having a highly developed society or culture; belonging to civilization.
Showing evidence of moral and intellectual advancement; humane, reasonable, ethical.
Marked by refinement in taste and manners.
Of a person: having obtained worldly experience, and lacking naiveté; cosmopolitan, worldly-wise.
Complicated, especially of complex technology.
Of art or other things: appealing to the tastes of an intellectual or sophisticated (sense 1) person; cerebral; also, cultured, elegant, refined.