Trouble, inconvenience.
Fuss, ado.
A mild expression of annoyance.
To do something which is of negligible inconvenience.
To feel care or anxiety; to make or take trouble; to be troublesome.
To annoy, to disturb, to irritate.
Severe fussiness and crying, especially of infants with certain medical conditions.
A medicinal plant used to relieve such symptoms.
Severe pains that grip the abdomen or the disease that causes such pains (due to intestinal or bowel-related problems).
Relating to the colon; colonic.