The distress that results from some disaster.
An event resulting in great loss.
A traumatic or stressful change in a person's life.
A crucial or decisive point or situation; a turning point.
A sudden change in the course of a disease, usually at which point the patient is expected to either recover or die.
A point in a drama at which a conflict reaches a peak before being resolved.
An unstable situation, in political, social, economic or military affairs, especially one involving an impending abrupt change.