To make harmless.
To surgically remove the claws of (an animal); to perform onychectomy on.
To bump lightly, whether accidentally or purposefully.
To change a mechanic, an ability or a character in a video game in order to make a previously dominant strategy less viable or less effective.
To arbitrarily limit or reduce the capability of.
The deterioration, weakening or worsening of a character, a weapon, a spell, etc.