To reduce by destroying or consuming the vital powers of; to exhaust, as a country of its strength or resources, a treasury of money, etc.
To empty or unload, as the vessels of the human system, by bloodletting or by medicine.
To shed, remove, discard, or eliminate.
To cause (somebody) to be unable to follow or trace one any longer.
To shed (weight).
To fail to catch with the mind or senses; to miss.
To cause (something) to cease to be in one's possession or capability due to unfortunate or unknown circumstances, events or reasons.
To have (an organ) removed from one's body, especially by accident.
To wander from; to miss, so as not to be able to find; to go astray from.
To cause (someone) the loss of something; to deprive of.
To fail to win (a game, competition, trial, etc).
To be unable to follow or trace (somebody or something) any longer.
To experience the death of (someone to whom one has an attachment, such as a relative or friend).
To be deprived of access to something.
To cease exhibiting; to overcome (a behavior or emotion).
To give or owe (money) after losing a bet.
Of a clock, to run slower than expected.