A reduction in the functionality of an organ caused by disease, injury or lack of use.
To cause to waste away or become abortive; to starve or weaken.
To wither or waste away.
Change for the worse; deterioration; morbid perversion.
Detraction; depreciation.
The state of being depraved or degenerated; degeneracy; depravity.
The act of depraving, or making anything bad; the act of corrupting.