To cause to malfunction or become inoperative.
To cause disorder in (something); to distort from its ideal state.
To cause (someone) to go insane or become deranged.
To involve in such complications as to render extrication difficult.
To ensnare.
To tangle up; to twist or interweave in such a manner as not to be easily separated.
To involve in difficulties or embarrassments; to embarrass, puzzle, or distract by adverse or perplexing circumstances, interests, demands, etc.; to hamper; to bewilder.