difficulty vs vicissitude

difficulty

noun
  • The state of being difficult, or hard to do. 

  • Physical danger from the environment, especially with risk of drowning 

  • An obstacle that hinders achievement of a goal. 

  • An objection. 

  • An awkward situation or quarrel. 

  • That which cannot be easily understood or believed. 

vicissitude

noun
  • A change, especially in one's life or fortunes. 

  • Regular change or succession from one thing to another, or one part of a cycle to the next; alternation; mutual succession; interchange. 

How often have the words difficulty and vicissitude occurred in a corpus of books? (source: Google Ngram Viewer )