Lack of ease; uneasiness; trouble; vexation; disquiet.
Any abnormal or harmful condition, as of society, people's attitudes, way of living etc.
An abnormal condition of a human, animal or plant that causes discomfort or dysfunction; distinct from injury insofar as the latter is usually instantaneously acquired.
To infect with a disease.
The inability to adapt oneself to the needs of others, or to the stresses of normal life.
A poor or faulty adjustment, especially of a mechanism.