Something considered indicative of feelings of pessimism and despair.
Destiny; often with a connotation of death, ruin, misfortune, etc.
An event or a situation which is inevitable in the fullness of time.
The mature endpoint of a region, group of cells or individual cell in an embryo, including all changes leading to that mature endpoint
The presumed cause, force, principle, or divine will that predetermines events.
The effect, consequence, outcome, or inevitable events predetermined by this cause.
The products of a chemical reaction in their final form in the biosphere.
To foreordain or predetermine, to make inevitable.