To betray or go back on.
To cross twice in hybridization, as (A × B) × (C × D); for example, in commercial hybrid seed corn, A through D are classically inbreds, and their grandoffspring is the seed for sale.
To cheat or swindle; to use crafty, deceitful methods. (often with "out of" preceding the object)
To obtain, arrange, or achieve by deceitful methods, by trickery.
To obtain, arrange, or achieve by indirect, complicated and/or intensive efforts.