An unforeseen event causing great loss, upset or unpleasantness of whatever kind.
An unexpected natural or man-made catastrophe of substantial extent causing significant physical damage or destruction, loss of life or sometimes permanent change to the natural environment.
Something or someone disagreeable, dispiriting or depressing; a killjoy.
A livestock animal that has collapsed.
A negative drug trip.
A form of industrial action in which workers down tools and refuse to work.
A drug that has depressant qualities.