Something or someone disagreeable, dispiriting or depressing; a killjoy.
A livestock animal that has collapsed.
A negative drug trip.
A form of industrial action in which workers down tools and refuse to work.
A drug that has depressant qualities.
Great sadness or depression, especially of a thoughtful or introspective nature.
Black bile, formerly thought to be one of the four "cardinal humours" of animal bodies.
Affected with great sadness or depression.