A drug that has depressant qualities.
A livestock animal that has collapsed.
A negative drug trip.
A form of industrial action in which workers down tools and refuse to work.
Something or someone disagreeable, dispiriting or depressing; a killjoy.
An agent or drug that sedates, having a calming or soothing effect, or inducing sleep.
Calming, soothing, inducing sleep, tranquilizing