enema vs vaccine

enema

noun
  • A device for administering such an injection. 

  • An injection of fluid into the large intestine by way of the rectum, usually for medical purposes. 

  • The fluid so injected. 

vaccine

noun
  • A substance given to stimulate a body's production of antibodies and provide immunity against a disease without causing the disease itself in the treatment, prepared from the agent that causes the disease (or a derivative of it; or a related, also effective, but safer disease), or a synthetic substitute; also, a dose of such a substance. 

  • Something defensive or protective in nature, like a vaccine (sense 1.1). 

  • Material taken from cowpox pustules used for vaccination against smallpox. 

  • A software program which protects computers against, or detects and neutralizes, computer viruses and other types of malware; an antivirus. 

  • The process of vaccination; immunization, inoculation. 

adj
  • Of, pertaining to, caused by, or characteristic of cowpox. 

  • Of or pertaining to cowpox as a source of material for vaccination against smallpox; also, of or pertaining to such material used for vaccination. 

How often have the words enema and vaccine occurred in a corpus of books? (source: Google Ngram Viewer )