To reduce to nothing, to destroy, to eradicate.
To render null and void; to abrogate.
To react with antimatter, producing gamma radiation and (for higher-mass reactants, especially composite particles such as protons) lighter particles (such as pions, muons, and neutrinos).
To eliminate completely; to annihilate.
To delete permanently (e-mail etc.) that was previously marked for deletion but still stored.
To erase or strike out.