Most importantly.
In front, prominently forward.
First in time.
Positioned in front of (all) others in space, most forward.
Coming before (all) others in time.
Closest to the bow.
Of the highest rank or position; of the greatest importance; of the highest priority.
likewise
To make a note of.
A question on a test, which may include its answers.
Two people who are having a romantic or sexual relationship with each other.
A line of text having a legal or other meaning; a separate particular in an account.
An object that can be picked up for later use.
A distinct physical object.
A short article in a newspaper.
A matter for discussion in an agenda.