Most importantly.
In front, prominently forward.
First in time.
Positioned in front of (all) others in space, most forward.
Coming before (all) others in time.
Closest to the bow.
Of the highest rank or position; of the greatest importance; of the highest priority.
To a great extent.
Often; frequently.
Used to indicate or compare extent.
A large amount or great extent.
Many ( + plural countable noun).
A large amount of.
Used to indicate, demonstrate or compare the quantity of something.