An unpleasant state of mental uneasiness, nervousness, apprehension and obsession or concern about some uncertain event.
An uneasy or distressing desire (for something).
A state of restlessness and agitation, often accompanied by a distressing sense of oppression or tightness in the stomach.
An abnormal skin sensation similar to that of insects crawling over or within the skin; a tactile hallucination involving such a sensation. A common side-effect of substance abuse, it can also be experienced with high fever, menopause, skin cancer, diabetic neuropathy, or herpes zoster.