To impair the physical or mental abilities of; to cause a serious, permanent injury.
To render unable; to take away an ability of, as by crippling.
To deactivate, to make inoperational (especially of a function of an electronic or mechanical device).
To drain emotionally or physically.
To fray or wear down, especially at the edges.
A burnt fragment; a cinder or crisp.
The condition or quality of being frazzled; a frayed end.