A drug addict.
A person who is extremely abnormal in appearance due to a severe medical condition (originally, a freak of nature); later extended to meaning a person who is extremely abnormal in social behavior, sexual orientation, gender identity, and/or business practices; an oddball, especially in physiology (e.g., "circus freak"); a unique person, originally in a displeasing or alienating way.
An enthusiast, or person who has an obsession with, or extreme knowledge of, something.
A person whose physique has grown far beyond the normal limits of muscular development; often a bodybuilder weighing more than 260 pounds (117.934 kilos).
A very sexually perverse individual.
A man, particularly a bold, strong, vigorous man.
A fellow; a petulant young man.
A hippie.
Strange, weird, unexpected.
To react extremely or irrationally, usually under distress or discomposure.
To be placed or place someone under the influence of a psychedelic drug, (especially) to experience reality withdrawal, or hallucinations (nightmarish), to behave irrational or unconventional due to drug use.