Morally reprehensible; clearly and grossly objectionable.
Damaged; poorly manufactured; injured.
In disarray or dishevelment (emotionally or otherwise).
Drunk; wasted; incredibly intoxicated (not necessarily with alcohol).
Misconstrued or misunderstood; taken the wrong way
In a screwed up or messed up manner; (by extension) under the influence of alcohol or drugs.
All wrong; mistaken; taken the wrong way
Morally reprehensible; clearly and grossly objectionable.
Having been screwed into a ball.
Broken, damaged, inoperative or having only partial functioning, especially by inept handling.
Having psychological problems; being mentally distraught or damaged.