To undo the integrity of, break into parts.
To cause to break up into infinitesimal parts through the use of a disintegrator.
To fall apart, break up into parts.
Of a person or entity, to cease to be reputable and instead become delinquent, criminal, immoral, corrupt or poorly behaved.
Of foods and commodities, to spoil, rot, or otherwise become unusable due to age or storage conditions.
Of a geographic area, to become unsafe.