Of a person or entity, having ceased to be reputable and having instead become delinquent, criminal, or poorly behaved.
Of a region or area, having become unsafe.
Of a delinquent or criminal act, having unexpectedly become more violent than is typical for that act—having resulted in an attack on a victim leading to serious injury or death.
Of foods and commodities, having become spoiled, rotten, or otherwise unusable due to age or storage conditions.
Breaching principles of natural law, rectitude, or justice, and so inconsistent with the demands of virtue, purity, or "good morals"; not right, not moral. (Compare unethical, illegal.)