Of a person or entity, having ceased to be reputable and having instead become delinquent, criminal, or poorly behaved.
Of a region or area, having become unsafe.
Of a delinquent or criminal act, having unexpectedly become more violent than is typical for that act—having resulted in an attack on a victim leading to serious injury or death.
Of foods and commodities, having become spoiled, rotten, or otherwise unusable due to age or storage conditions.
In a lifestyle, employment position, or other set of circumstances where the rapid pace is exciting, frantic, or risky.