That which causes despair.
Loss of hope; utter hopelessness; complete despondency.
That which is despaired of.
To be hopeless; to have no hope; to give up all hope or expectation.
To cause to despair.
Suffering, hardship.
Emotional pain, generally arising from misfortune, significant personal loss, bereavement, misconduct of oneself or others, etc.; sorrow; sadness.
Cause or instance of sorrow or pain; that which afflicts or distresses; trial.
To deliberately harass and annoy or cause grief to other players of a game in order to interfere with their enjoyment of it; especially, to do this as one’s primary activity in the game.