A problem that is challenging to solve.
Used other than figuratively or idiomatically: see hard, nut, crack.
A situation, person, group, etc. which is difficult to overcome or deal with.
A place, opportunity, etc. to which it is difficult to gain entry.
An amount that is difficult to finance.
A difficulty.
In the Odonata, a prominent crossvein near the centre of the leading edge of a wing.