Trouble, inconvenience.
Fuss, ado.
A mild expression of annoyance.
To do something which is of negligible inconvenience.
To feel care or anxiety; to make or take trouble; to be troublesome.
To annoy, to disturb, to irritate.
detriment; misfortune.
physical injury; hurt; damage
That which causes injury, damage, or loss.
emotional or figurative hurt
To cause injury to another; to hurt; to cause damage to something.