To negatively criticize.
To put a damper on (a mood).
Severe or cruel.
Unpleasantly rough to the touch or other senses.
Not any thing; no thing.
An absence of anything, including empty space, brightness, darkness, matter, or a vacuum.
Something trifling, or of no consequence or importance.
A trivial remark especially in the term sweet nothings.
A nobody (insignificant person).