To cast a spell upon.
To fascinate or charm.
To astonish, amaze.
To cast a spell on (specifically an evil spell), to bewitch.
A spell (now rare but still found in compounds such as hex sign and hexcraft).
A hexagonal space on a game board.
An evil spell or curse.
A witch.
a hexagon-shaped item of rock climbing equipment intended to be wedged into a crack or other opening in the rock.