A witch.
A spell (now rare but still found in compounds such as hex sign and hexcraft).
A hexagonal space on a game board.
An evil spell or curse.
a hexagon-shaped item of rock climbing equipment intended to be wedged into a crack or other opening in the rock.
To cast a spell on (specifically an evil spell), to bewitch.
In South African English, a wizard, witch, or a spiteful person who operates in secret to harm others or who uses poisons and familiar spirits to carry out harmful deeds.