in it vs up against it

in it

prep
  • In trouble. 

  • Taking part in something, such as a lottery. 

  • Having an expected payout or reward. 

  • Getting on successfully, especially in a game. 

up against it

prep
  • In a very difficult position. 

How often have the words in it and up against it occurred in a corpus of books? (source: Google Ngram Viewer )